Manchester City visit Turf Moor on Wednesday seeking a win that would take them to the top of the Premier League table - a result that would also relegate Burnley.
The omens are not good. Burnley have won just one of their 19 Premier League games against City and have lost the past 11, which is their longest-ever losing league run against another team.
Scott Parker's side are also winless in their past 12 home Premier League matches, the club's second-worst run without winning at Turf Moor in their league history.
And they come into this match on the back of a 4-1 capitulation at fellow strugglers Nottingham Forest. Head coach Parker said the boos from Burnley supporters at the City Ground were justified, admitting that they "saw a team just fall away".
That was Burnley's second-heaviest defeat of the season - topped only by the 5-1 thumping by City at Etihad Stadium in September. It could be another long 90 minutes for Clarets fans.
Before City visited West Ham on 14 March, Pep Guardiola said his side's title hopes would be over if they dropped points. When they did just that in a 1-1 draw, it meant City were nine points adrift of Premier League leaders Arsenal, with one game in hand.
If City win at Burnley, they will take over at the top of the Premier League with both they and Arsenal having just five matches left to play.
It has been a fascinating and thrilling title run-in and there will surely be a few more twists yet before the Premier League season concludes on 24 May.
But City's win over Arsenal on Sunday suggests Guardiola has got his team going at just the right time and when it really matters, something he has made a habit of.
Since Mikel Arteta's first league game in charge of Arsenal in 2019, the Gunners have been top for 539 days to City's 453. Yet in that time, City have collected four Premier League titles while Arsenal have won none.
