Lazio head coach Maurizio Sarri is gearing up for a major shake-up in Saturday's Serie A clash against Inter Milan, with a heavily rotated lineup expected to take the field. Both teams have one eye on Wednesday's Coppa Italia final, making this weekend's match a dress rehearsal with a twist.

According to reports from La Lazio Siamo Noi, Sarri is planning at least five changes from the side that edged past Cremonese 2-1 on Monday. The defense is set for a complete overhaul, with only Alessio Romagnoli likely to keep his spot in the backline. The experienced center-back is expected to start ahead of Oliver Provstgaard, who may enter later in the game.

Mario Gila is poised for an immediate return to the starting XI after recovering from his latest injury setback, while Manuel Lazzari and Luca Pellegrini will step in for Adam Marusic and Nuno Tavares at full-back. In midfield, Nicolo Rovella is tipped to make his first start since returning from collarbone surgery, though he's not yet fit for a full 90 minutes—Patric is likely to take over in the second half.

Toma Basic will fill one of the box-to-box roles, while Kenneth Taylor could be rested for the first time since joining the club. If so, Fisayo Dele-Bashiru would get the nod. In attack, Matteo Cancellieri returns from suspension but is expected to start on the bench, with Gustav Isaksen keeping his place on the right wing.

On the left flank, Pedro should replace Mattia Zaccagni, whose latest training session ended early due to a knock. It remains unclear if the Lazio captain will be fit enough for a call-up. Up front, Daniel Maldini is the favorite for the center-forward role, as Tijjani Noslin could be preserved for the final. However, Boulaye Dia is also in the running to start.

With Sarri's rotation strategy in full swing, Saturday's match promises to be a tactical battle as both sides look to fine-tune their game plans ahead of the Coppa Italia showdown.