The stage is set for a dramatic European night as Mainz 05 travel to face RC Strasbourg Alsace, holding a precious 2-0 aggregate lead. A spot in the Europa Conference League semi-finals is within touching distance for Urs Fischer's men, who struck early in the home leg through Kaishu Sano and Stefan Posch.

Strasbourg arrive rested, having seen their weekend Ligue 1 fixture postponed to aid French clubs' European coefficient. Mainz, however, come in off a narrow Bundesliga defeat to Freiburg, a result that may sharpen their focus as they look to make history. This quarter-final run is already Mainz's deepest ever in European competition and the best by any German side in the Conference League era.

Team news brings a major boost for the visitors, with creative spark Nadiem Amiri returning from injury with a 30-minute appearance against Freiburg, putting him in contention for a start. Strasbourg will look to their own attacking talents, like Julio Enciso, to overturn the deficit and ignite the home crowd at the Stade de la Meinau.

Predicted Lineups:
Strasbourg: Penders; Doue, Omobamidele, Doukoure ©, Chilwell; El Mourabet, Barco; Yassine, Oyedele, Godo; Enciso
Mainz: Batz; da Costa, Posch, Kohr; Widmer ©, Sano, Mwene; Nebel, Kawasaki; Amiri, Tietz