Mets vs. Cubs prediction, odds, time: 2026 MLB picks for Friday, April 17 from proven model

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Mets vs. Cubs prediction, odds, time: 2026 MLB picks for Friday, April 17 from proven model

Mets vs. Cubs prediction, odds, time: 2026 MLB picks for Friday, April 17 from proven model

SportsLine's model simulated New York Mets vs. Chicago Cubs 10,000 times and revealed its MLB picks for Friday's matchup

Mets vs. Cubs prediction, odds, time: 2026 MLB picks for Friday, April 17 from proven model

SportsLine's model simulated New York Mets vs. Chicago Cubs 10,000 times and revealed its MLB picks for Friday's matchup

The New York Mets, mired in an eight-game losing streak, head to the iconic Wrigley Field this Friday to open a three-game set against the Chicago Cubs. The Mets are reeling, having just been swept by both the Dodgers and Athletics, while the Cubs are looking to build momentum after taking a series from the Phillies.

On the mound, the pitching matchup presents a stark contrast. The Mets will send Kodai Senga (0-2, 7.07 ERA) to the hill, hoping he can find his form against a Cubs lineup that has been inconsistent at home. Chicago counters with Edward Cabrera (1-0, 1.62 ERA), who has been brilliant early this season. First pitch is scheduled for 2:20 p.m. ET, with the Cubs installed as -157 favorites on the money line and the over/under set at 10.5 runs.

For those analyzing the matchup, a proven computer model from SportsLine has simulated this game 10,000 times. This model, which was highly profitable on money-line picks and home run props last season, has identified a strong trend for Friday's contest. The model is leaning heavily toward the Under, noting the total has stayed below the number in four of the Mets' last six games. With two teams looking to establish rhythm early in the season, this could be a pitcher's duel at the Friendly Confines.

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