The Cleveland Cavaliers face a significant test on the road Friday night against the Atlanta Hawks, and they might have to navigate it without their two biggest stars. Donovan Mitchell and Jarrett Allen headline a concerning injury report that could force major adjustments for a team looking to solidify its playoff positioning.

Mitchell, the Cavs' explosive scoring leader, has been ruled out for ankle injury management. This marks his first missed game since early April, leaving a massive void in the backcourt. In his absence, expect increased offensive responsibility to fall on the shoulders of James Harden and Evan Mobley, while wings like Keon Ellis and Max Strus could see expanded roles.

The challenges compound in the frontcourt, where All-Star center Jarrett Allen will also sit for knee injury management. With backup Thomas Bryant also ruled out (calf), Cleveland's interior defense and rebounding will be severely tested. Veteran Larry Nance Jr. is the most likely candidate to step into a starting role and absorb major minutes against Atlanta's Clint Capela.

Further depleting the rotation, sharpshooter Sam Merrill is out with a hamstring issue. There is a potential bright spot, however, as rookie Jaylon Tyson is listed as questionable and could return from a 10-game absence due to a toe injury, offering a possible boost to the wing depth.

Coming off a home win against these same Hawks on Wednesday, the Cavaliers now face a much tougher task of securing a road victory while severely shorthanded. How the role players respond will be crucial as Cleveland aims to protect its 51-29 record. Tip-off from Atlanta is set for 7:00 p.m. ET on Amazon Prime Video.