Dodgers vs Giants Prediction: Odds, recent stats, trends, and best bets for April 21

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Dodgers vs Giants Prediction: Odds, recent stats, trends, and best bets for April 21

Los Angeles Dodgers vs San Francisco Giants Game Preview

Dodgers vs Giants Prediction: Odds, recent stats, trends, and best bets for April 21

Los Angeles Dodgers vs San Francisco Giants Game Preview

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The San Francisco Giants (9-13) host the Los Angeles Dodgers (16-6) at Oracle Park for a three-game series.

Los Angeles split the series with Colorado, but is coming off a 12-3 win. The Dodgers outscored the Rockies, 28-17 despite going 2-2. The Dodgers lead the MLB in batting average (.293), home runs (42), RBI (128), and hits (222).

San Francisco had its three-game winning streak snapped in a 3-0 loss to Washington on Sunday. The Giants will need more offense against the Dodgers. San Francisco is hitting the fewest amount of home runs (13) despite having the 10th-best batting average (.251).

Let's dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Moneyline: Los Angeles Dodgers (-86), San Francisco Giants Rockies (+153)

Monday’s pitching matchup (April 20): Landen Roupp vs. Yoshinobu Yamamoto

2026 stats: 25.2 IP, 2-1, 2.10 ERA, 0.82 WHIP, 21 Ks, 3 BB

2026 Stats: 22.2 IP, 3-1, 2.38 ERA, 0.97 WHIP, 24 Ks, 7 BB

The Giants’ Luis Arraez is hitting .305 with 25 hits and 30 total bases over 82 at-bats

The Giants’ Harrison Bader is hitting .115 with 6 hits and 17 strikeouts over 52 at-bats

The Dodgers’ Andy Pages is hitting .370 with 30 hits and 49 total bases over 81 at-bats

The Dodgers’ Alex Freeland is hitting .218 with 12 hits and 19 strikeouts over 55 at-bats

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Dodgers at Giants

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Dodgers and the Giants

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

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