The Arizona Diamondbacks are riding high after Ildemaro Vargas' four-hit performance, and they'll look to carry that momentum into Saturday's matchup against the Chicago Cubs at Wrigley Field.

Vargas has been a force at the plate this season, leading the Diamondbacks with a .404 batting average to go along with six home runs and 21 RBIs. He'll be a key figure as Arizona (16-15) looks to snap out of a rough stretch—the Diamondbacks have dropped seven of their last 10 games and have been outscored by 28 runs during that span.

The Cubs, meanwhile, come into this one as one of the hottest teams in baseball. Chicago (20-12) holds the best record in the NL Central and has won seven of their last 10 contests. They've been especially tough at home, posting a 12-5 record at Wrigley Field. The Cubs' offense ranks fifth in MLB with a .425 slugging percentage, and Seiya Suzuki has been on a tear—going 14-for-36 with five home runs and seven RBIs over his last 10 games.

Saturday's pitching matchup features two right-handers with contrasting seasons so far. Ryne Nelson (1-2, 7.71 ERA) will take the mound for Arizona, while Shota Imanaga (2-2, 3.15 ERA) gets the nod for Chicago. Imanaga has been sharp with a 0.87 WHIP and 38 strikeouts, while Nelson has struggled to find consistency.

Nolan Arenado has been a bright spot for the Diamondbacks lately, going 13-for-32 with two home runs and six RBIs in his last 10 games. For the Cubs, Nico Hoerner leads the team with a .297 average and has added four home runs, though he's listed as day-to-day with a neck issue.

Both teams are dealing with significant injuries. The Cubs have a lengthy list that includes Justin Steele and Porter Hodge on the 60-day IL, while the Diamondbacks are without Carlos Santana (groin) and Jordan Lawlar (wrist), among others.

First pitch is set for Saturday afternoon, with the Cubs listed as -168 favorites and the over/under at 7.5 runs.