The NFL schedule release is just around the corner, and Arizona Cardinals fans are already buzzing with early rumors. According to PHNX’s Johnny Venerable and multiple sources, the Cardinals are expected to kick off the 2026 season on the road—heading to SoFi Stadium to face the Los Angeles Chargers in Week 1.

This matchup would mark the first of two trips to Inglewood, California, this season. The Cardinals are also slated to take on the Los Angeles Rams in their annual divisional showdown, meaning SoFi will feel like a second home for Arizona fans.

Opening against the Chargers sets the stage for an intriguing test right out of the gate. The Chargers are known for their explosive offense and young talent, making this a must-watch opener that could set the tone for the Cardinals’ campaign. For Arizona, it’s a chance to make an early statement on the road.

Here’s a quick look at the Cardinals’ full 2026 home and away opponents:

Home: San Francisco 49ers, Los Angeles Rams, Seattle Seahawks, Chicago Bears, Detroit Lions, New Orleans Saints, Tampa Bay Buccaneers, and one AFC opponent (to be determined).

Away: San Francisco 49ers, Los Angeles Rams, Seattle Seahawks, Atlanta Falcons, Carolina Panthers, Green Bay Packers, Minnesota Vikings, and the Los Angeles Chargers.

As the official schedule release nears, expect more clarity on game times and primetime slots. Whether you’re gearing up for the season with new Cardinals gear or just excited for the action, this opener promises to be a thrilling start to what could be a pivotal year for the team.