In a night that had all the makings of a masterpiece, Milwaukee Brewers flamethrower Jacob Misiorowski was forced to exit his May 1 start against the Washington Nationals with what the team described as a right hamstring cramp.

The 23-year-old right-hander was in the midst of a no-hitter when he signaled discomfort after throwing a 98.9 mph fastball to James Wood in the bottom of the sixth inning. Manager Pat Murphy and head athletic trainer Brad Epstein quickly visited the mound, and after a brief conversation, Misiorowski was pulled in favor of reliever Aaron Ashby.

It was a sudden end to what had been a dominant performance. Misiorowski retired 11 straight batters after walking Brady House in the second inning, and he seemed to get stronger as the game progressed. He struck out the side in the fifth on just 11 pitches and was still touching 101.5 mph with his fastball. Through 5⅓ innings, he allowed no hits, walked two, and struck out eight over 85 pitches.

According to MLB researcher Sarah Langs, Misiorowski threw 43 pitches of 100 mph or more — the third-most in any individual start since pitch tracking began in 2008. It was the kind of electric stuff that makes him one of the most exciting young arms in baseball.

The no-hitters streak ultimately ended with one out in the seventh when Daylen Lile doubled. But the Brewers held on for a 4-1 lead at the time.

The early exit marks the second consecutive day a Brewers starter has left a game prematurely. Brandon Woodruff departed his April 30 start in the second inning and was placed on the injured list with shoulder inflammation 24 hours later.

Misiorowski came into the night with a 3.31 ERA and a league-leading 51 strikeouts over six starts, cementing his reputation as a rising star. While the cramp appears minor, Brewers fans will be holding their breath until more updates emerge on their young ace.