Wednesday night's Copa Sudamericana action delivered drama, shock results, and a major statement from an underdog. Here are the key takeaways from a matchday that reminded us why South American football is so unpredictable.

The undisputed headline was written in Uruguay, where Montevideo City Torque pulled off a stunning 1-0 victory over Brazilian giants Grêmio. Eduardo Agüero's goal secured a famous win, propelling Torque to the top of their group and serving a notice that they are a force to be reckoned with.

Meanwhile, River Plate's campaign hit an early snag in Bolivia. Despite playing at an altitude-friendly venue and taking the lead through Sebastián Driussi, Lucas Martínez Quarta's red card proved pivotal. Jorge Vásquez's equalizer for Always Ready forced River to settle for a 1-1 draw, a frustrating start for El Millonario.

The surprises continued as Santos, without the injured Neymar Jr., fell to a 1-0 defeat against Ecuador's Deportivo Cuenca. A costly own goal by goalkeeper João Paulo handed Cuenca the victory, allowing them to climb to the summit of Group G after San Lorenzo and Recoleta played to a draw. It was a night that proved in the Sudamericana, no favorite is ever truly safe.