The NFL is set to drop the full 2026 schedule for all 32 teams in the coming days, with announcements reportedly expected sometime next week. While every team has known their opponents and home/away designations for months, the exact order of games has remained a mystery—until now.
With the schedule release on the horizon, NFL.com has already ranked the top 10 matchups to watch next season, and the Buffalo Bills appear twice on that list. That’s no surprise for a team that’s become appointment viewing in recent years.
Coming in at the No. 5 spot is Buffalo’s road trip to face the New England Patriots. But the real headliner lands at No. 2: the Bills hosting the Kansas City Chiefs at the brand-new Highmark Stadium. Whenever Patrick Mahomes and Josh Allen share a field, football fans know to clear their calendars. This clash of future Hall of Fame quarterbacks carries extra weight this time around.
Mahomes is recovering from a torn ACL, and the Chiefs missed the playoffs in 2025—a rare stumble that has raised the stakes in Kansas City. Meanwhile, Travis Kelce may be playing his final NFL season, adding an emotional layer to the matchup. On the other side, the Bills are hungry after losing the AFC East crown last year and failing to capitalize on a wide-open playoff field.
These two teams have met 10 times in the 2020s, splitting the series 5-5. Buffalo has dominated the regular season with a 5-1 record, but the Chiefs hold a perfect 4-0 mark in playoff meetings. This game at the new Highmark Stadium promises to be one of the most anticipated battles of the 2026 season—just as it has been for nearly a decade.
As for the Patriots game, the rivalry is heating up again. New England reclaimed the AFC East in 2025 but lost their home game against Buffalo, making this rematch critical for both teams. Drake Maye outplayed Josh Allen in their last meeting, and Maye’s emergence as an MVP candidate has only added fuel to this division rivalry. Whether you’re a Bills fan or just love great football, these two matchups are must-watch TV.